Direct Link Immune System And The Brain — Profound Implications For Neurology

 Direct Link Immune System And The Brain – Vessels Found By Antoine Louveau, PhD,
Posted: 01 Jun 2015 09:24 AM PDT
In a stunning discovery that overturns decades of textbook teaching, researchers have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. The discovery could have profound implications for diseases from autism to Alzheimer’s to multiple sclerosis.

“Instead of asking, ‘How do we study the immune response of the brain?’ ‘Why do multiple sclerosis patients have the immune attacks?’ now we can approach this mechanistically. Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,” said Jonathan Kipnis, PhD, professor in the UVA Department of Neuroscience and director of UVA’s Center for Brain Immunology and Glia (BIG). “It changes entirely the way we perceive the neuro-immune interaction. We always perceived it before as something esoteric that can’t be studied. But now we can ask mechanistic questions.”

“We believe that for every neurological disease that has an immune component to it, these vessels may play a major role,” Kipnis said. “Hard to imagine that these vessels would not be involved in a [neurological] disease with an immune component.” …

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Missing link found between brain, immune system; major disease implications

University of Virginia Health System. “Missing link found between brain, immune system; major disease implications.” ScienceDaily. ScienceDaily, 1 June 2015. <www.sciencedaily.com/releases/2015/06/150601122445.htm>.
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Antoine Louveau, Igor Smirnov, Timothy J. Keyes, Jacob D. Eccles, Sherin J. Rouhani, J. David Peske, Noel C. Derecki, David Castle, James W. Mandell, Kevin S. Lee, Tajie H. Harris, Jonathan Kipnis. Structural and functional features of central nervous system lymphatic vessels. Nature, 2015; DOI: 10.1038/nature14432

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Lather

Lather—- Jefferson Airplane  — Crown of Creation  1968

Written By: Grace Slick

Grace Slick – Lead Vocals
Jorma Kaukonen – Lead Guitar
Paul Kantner – Rhythm Guitar
Jack Casady – Bass Guitar
Spencer Dryden – Drums,

Lather was thirty years old today,
They took away all of his toys.
His mother sent newspaper clippings to him,
About his old friends who’d stopped being boys.
There was Harwitz E. Green, just turned thirty-three,
His leather chair waits at the bank.
And Sergeant Dow Jones, twenty-seven years old,
Commanding his very own tank.
But Lather still finds it a nice thing to do,
To lie about nude in the sand,
Drawing pictures of mountains that look like bumps,
And thrashing the air with his hands.

But wait, oh Lather’s productive you know,
He produces the finest of sound,
Putting drumsticks on either side of his nose,
Snorting the best licks in town, But that’s all over…
Lather was thirty years old today,
And Lather came foam from his tongue.
He looked at me eyes wide and plainly said,
Is it true that I’m no longer young?
And the children call him famous, what the old men call insane,
And sometimes he’s so nameless,
That he hardly knows which game to play…
Which words to say…
And I should have told him, “No, you’re not old.”
And I should have let him go on…smiling…baby-wide