Direct Link Immune System And The Brain — Profound Implications For Neurology

 Direct Link Immune System And The Brain – Vessels Found By Antoine Louveau, PhD,
Posted: 01 Jun 2015 09:24 AM PDT
In a stunning discovery that overturns decades of textbook teaching, researchers have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. The discovery could have profound implications for diseases from autism to Alzheimer’s to multiple sclerosis.

“Instead of asking, ‘How do we study the immune response of the brain?’ ‘Why do multiple sclerosis patients have the immune attacks?’ now we can approach this mechanistically. Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,” said Jonathan Kipnis, PhD, professor in the UVA Department of Neuroscience and director of UVA’s Center for Brain Immunology and Glia (BIG). “It changes entirely the way we perceive the neuro-immune interaction. We always perceived it before as something esoteric that can’t be studied. But now we can ask mechanistic questions.”

“We believe that for every neurological disease that has an immune component to it, these vessels may play a major role,” Kipnis said. “Hard to imagine that these vessels would not be involved in a [neurological] disease with an immune component.” …

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Missing link found between brain, immune system; major disease implications

University of Virginia Health System. “Missing link found between brain, immune system; major disease implications.” ScienceDaily. ScienceDaily, 1 June 2015. <www.sciencedaily.com/releases/2015/06/150601122445.htm>.
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Antoine Louveau, Igor Smirnov, Timothy J. Keyes, Jacob D. Eccles, Sherin J. Rouhani, J. David Peske, Noel C. Derecki, David Castle, James W. Mandell, Kevin S. Lee, Tajie H. Harris, Jonathan Kipnis. Structural and functional features of central nervous system lymphatic vessels. Nature, 2015; DOI: 10.1038/nature14432

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Choke The Stars

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.
Thick black
Fear Washes
Red over
the stars
Coalescing
Turning
Purple
A million
Dazzling
Pinwheels
Behind
My eyes
Below
Ground
Below oceans
Darkness
Erupting
Swirling
To blackness
Beneath
Movement
All around
Resonates
Roars
Too aware
Too much
Hot
A million
Electric
Fires burn
Each synapse
Arching
I leap
And jig
And dance
And cry
Silent
Until oily
Screams
Ululate
Terror
Chokes
The stars
Chokes
The sky
Starves
Song
There is
Nowhere
Without
Dread
And the
Black fires
Overtake
And I
Succumb
And everywhere
Is
Myself
I am
All memory
Not insane
And there is
No death
And there
Is no
Escape
And there is
No hope
And there is
No eternity
And there is
Nothing
.
.
.
Bear … 10.24.2014
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